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. 2020 Jan 28;9(2):84. doi: 10.3390/pathogens9020084

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The P. insignis extract and fractions reduced the lysosomal integrity of C. albicans and C. glabrata cells after 24 h of treatment. Data are shown as the relative fluorescence intensity (A) and histograms (B). Data were analyzed by ANOVA, followed by Tukey’s post-test, and statistical differences are represented by an asterisk. * p < 0.05. MIC, minimum inhibitory concentration; PiHE, hydroethanolic extract of P. insignis; DCMF, dichloromethane fraction; and EAF, ethyl acetate fraction.