Integrative and conjugative elements detected in the genomes of S. suis strains belonging to serotype 2. Strains belonging to LultiLocus-Sequence-Typing (MLST) groups ST25 (n = 51, with a blue frame) and ST28 (n = 51, with a red frame) appear separately. Only ICEs with a full sequence are shown in the figure. Boxes located in front of a strain name are either empty (absence of ICE) or colored (presence of an ICE). Boxes in the outer circle, middle circle, and inner circle, correspond to ICEs belonging to Tn5252, Tn154,9 and TnGBS2 families, respectively. The color of the box indicates the integration site of the element: yellow for integration into the 3′ end of rplL, salmon for integration into rumA, dark red for integration into mutT, purple for integration into the 5′ end of rbgA, dark brown for the lower specificity of TnGBS2.