Table 3.
Clinical characteristics of 13 Chinese melanoma patients in stage IV who received anti-PD-1 treatment.
| Patient | Sex | Age | Tumor site | Metastasis site | PD-1 antibody | Cycles | Efficacy | PD-L1 expression | IGFBP2 expression |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Female | 57 | Mucous | Lymph node | Opdivo | 2 | SD | Low | Low |
| 2 | Male | 64 | Mucous | Left adrenal gland | Keytruda | 4 | PD | High | Low |
| 3 | Male | 61 | Derma | Right lung | Keytruda | 2 | SD | High | High |
| 4 | Female | 42 | Derma | Right adrenal gland | Keytruda | 5 | PD | Low | High |
| 5 | Male | 60 | Derma | Right lung | Keytruda | 4 | PR | High | High |
| 6 | Female | 57 | undetermined origin | Right subaxillary | Keytruda | 2 | PD | Low | High |
| 7 | Male | 53 | Derma | Lymph node | Opdivo | 2 | SD | – | – |
| 8 | Female | 53 | Mucous | Lymph node | Keytruda | 3 | – | – | – |
| 9 | Female | 76 | Derma | Left lung | Keytruda | 21 | – | – | |
| 10 | Female | 59 | Mucous | Lymph node | Keytruda | 4 | – | – | – |
| 11 | Female | 50 | Mucous | Liver | Opdivo | 8 | – | – | – |
| 12 | Female | 57 | Mucous | Lung | Keytruda | 2 | – | – | – |
| 13 | Male | 62 | Derma | Liver | Keytruda | 7 | – | – | – |
Abbreviations: PR, partial response; SD, stable disease; PD, progression disease.