Fig. 5.

The photoacoustic imaging results. (a) In vitro PA imaging results and (b) Linear relationship between PA signal and concentration of the anti-VEGFR conjugated FePt nanoparticles. (c) In vivo PA imaging of tumor tissue before and after tail injection of the anti-VEGFR conjugated FePt nanoparticles under 900 nm laser irradiation at different time points (0, 0.5, 1, 2, 4 and 6 h post-injection). (d) Normalized PA signals in tumors at different time points. (e) In vivo PA imaging of region without tumor before and after tail injection of the anti-VEGFR conjugated FePt nanoparticles under 900 nm laser irradiation at different time points (0, 0.5, 1, 2, 4 and 6 h post-injection). (f) Normalized PA signals in region without tumor at different time points.