Table 2.
Clinical characteristics of SLE patients with cSLE versus late-onset SLE
| Clinical items | At diagnosis |
p-Value | Ever |
p-Value | ||
|---|---|---|---|---|---|---|
| cSLE (N = 57) | Late-onset SLE (N = 135) | cSLE (N = 57) | Late-onset SLE (N = 135) | |||
| Arthritis, n (%) | 35 (61.4) | 95 (70.4) | 0.22 | 45 (78.9) | 109 (80.8) | 0.77 |
| Acute cutaneous lupus, n (%) | 41 (71.9) | 84 (62.2) | 0.19 | 47 (82.4) | 87 (64.4) | 0.013 |
| Chronic cutaneous lupus, n (%) | 6 (10.5) | 15 (11.1) | 0.90 | 6 (10.5) | 15 (11.1) | 0.90 |
| Oral/nasal ulcers, n (%) | 12 (21.1) | 13 (9.6) | 0.055 | 20 (35.1) | 18 (13.3) | <0.001 |
| Non-scarring alopecia, n (%) | 12 (21.2) | 24 (17.8) | 0.59 | 22 (38.6) | 31 (23.0) | 0.026 |
| Lupus nephritis, n (%) | 8 (14.0) | 19(14.1) | 0.46 | 22 (38.6) | 24 (17.8) | 0.002 |
| Primary NPSLE, n (%) | 7 (12.3) | 19 (14.1) | 0.74 | 10 (17.6) | 23 (17.1) | 0.93 |
| Serositis, n (%) | 9 (15.8) | 23 (17.0) | 0.83 | 10 (17.6) | 29 (21.4) | 0.53 |
| Leucopaenia, n (%) | 19 (33.3) | 31 (23.0) | 0.13 | 26 (45.6) | 43 (31.9) | 0.07 |
| Thrombocytopaenia, n (%) | 7 (12.3) | 21 (15.6) | 0.55 | 13 (22.8) | 24 (17.8) | 0.42 |
| Raynaud’s, n (%) | 17 (29.8) | 50 (36.3) | 0.33 | 21 (36.8) | 51 (37.0) | 0.90 |
| Fever, n (%) | 23 (40.4) | 17 (12.6) | <0.0001 | 25 (43.9) | 20 (14.8) | <0.001 |
Statistically significant values are shown in bold.
SLE: systemic lupus erythematosus; cSLE: childhood-onset SLE.