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. 2020 Apr 20;20:176. doi: 10.1186/s12887-020-02028-6

Table 4.

Summary of subgroup analysis for the incidence of graft failure

Subgroup Cut-off value (μM*min/L) RR (95% CI) Number of studies Number of participants in treatment group Number of participants in control group I2%
Administration route IV Bu ≤800 versus> 800 11.282 (0.930, 136.897) 2 2 36 0
≤900 versus> 900 9.718 (1.499, 62.989) 4 10 150 0
≤1000 versus> 1000 0.418 (0.030, 5.850) 2 23 15 0
≤1225 versus> 1225 0.139 (0.011, 1.729) 2 32 6 0
Oral Bu ≤800 versus> 800 3.904 (0.800,19.055) 2 20 42 0
≤900 versus> 900 2.613 (0.869,7.860) 3 49 66 0
≤1000 versus> 1000 2.189 (0.328,14.587) 2 39 23 0
≤1225 versus> 1225 1.197 (0.186,7.720) 2 46 16 0

CI Confidence interval, NA Not applicable, IV Intravenous