Table 4.
Subgroup | Cut-off value (μM*min/L) | RR (95% CI) | Number of studies | Number of participants in treatment group | Number of participants in control group | I2% | |
---|---|---|---|---|---|---|---|
Administration route | IV Bu | ≤800 versus> 800 | 11.282 (0.930, 136.897) | 2 | 2 | 36 | 0 |
≤900 versus> 900 | 9.718 (1.499, 62.989) | 4 | 10 | 150 | 0 | ||
≤1000 versus> 1000 | 0.418 (0.030, 5.850) | 2 | 23 | 15 | 0 | ||
≤1225 versus> 1225 | 0.139 (0.011, 1.729) | 2 | 32 | 6 | 0 | ||
Oral Bu | ≤800 versus> 800 | 3.904 (0.800,19.055) | 2 | 20 | 42 | 0 | |
≤900 versus> 900 | 2.613 (0.869,7.860) | 3 | 49 | 66 | 0 | ||
≤1000 versus> 1000 | 2.189 (0.328,14.587) | 2 | 39 | 23 | 0 | ||
≤1225 versus> 1225 | 1.197 (0.186,7.720) | 2 | 46 | 16 | 0 |
CI Confidence interval, NA Not applicable, IV Intravenous