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. 2020 Apr 19;18:61. doi: 10.1186/s12951-020-00616-3

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 8 — Distribution of DiR-labeled empty micelles (DiPM) in ICH mice, assessed at 12 and 24 h after tail vein injection into mice with ICH. Key organs were removed and examined using an IVIS system. a DiPM accumulated at the hemorrhagic site at much higher level than free DiR. Images show the fluorescence intensity as an overlay in accordance with the scale. b Quantitation of DiR and DiPM in brain at 12 and 24 h after injection. **P < 0.01 (n=3)