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CONSORT flowchart. A total of 53 subjects were eligible and enrolled. Twelve subjects were enrolled in the single 325 mg acetylsalicylic acid (ASA) cohort, and one subject was excluded because salicylate was detected in the baseline (pre-ASA) plasma sample. Twenty-one and 20 subjects were enrolled in the sub-chronic 325 mg and 81 mg ASA cohorts, respectively. All data from these 41 subjects were analyzed.
