Table 5.

Cell proliferation inhibition data (IC₅₀). All experiments to determine IC₅₀ values were performed with at least triplicates at each compound dilution, and all IC₅₀ values were averaged when determined in two or more independent experiments. * Values previously published in Ravez et al. [25].

	Tumor Cell Lines
	PHGDH-Dependent	PHGDH-Independent	Normal Cell Line
	BT-20	MDA-MB-231	BJ-5ta
1	67.8 µM	>100 µM *	>100 µM
2	21.3 µM	>100 µM *	>100 µM
38	42.2 µM	>100 µM	>100 µM
39	>100 µM	>100 µM	>100 µM
NCT-503	6.52 µM	>100 µM	>100 µM