Table 1.
Baseline variables and risk of hospitalization
| Characteristic | N = 270, n (%) | OR (95% CI) | P-value |
|---|---|---|---|
| Patient Characteristics | |||
| Agea (years) | |||
| Median | 66.6 | 1.0 (1.0–1.0) | 0.80 |
| Range | 31–88 | ||
| Gender | |||
| Female (reference) | 134 (49.6) | ||
| Male | 136 (50.4) | 1.1 (0.6–2.1) | 0.69 |
| Race | |||
| Black (reference) | 76 (28.1) | ||
| Caucasian | 168 (62.2) | 1.4 (0.7–2.8) | 0.39 |
| Other | 26 (9.6) | 0.10 (0.01–1.8) | 0.12 |
| Marital Status | |||
| Partnered (reference) | 163 (60.4) | ||
| Un-partnered | 107 (39.6) | 0.8 (0.4–1.5) | 0.41 |
| Tumor Characteristics | |||
| Stage Summary | |||
| I-III (reference) | 206 (76.3) | ||
| IV | 32 (11.9) | 0.9 (0.3–2.4) | 0.79 |
| Loco-regional recurrence | 32 (11.9) | 0.7 (0.2–2.0) | 0.50 |
| Histology | |||
| Adenocarcinoma (reference) | 144 (53.3) | ||
| Squamous cell carcinoma | 88 (32.6) | 1.9 (1.0–3.8) | 0.06 |
| Small cell carcinoma | 11 (4.1) | 1.7 (0.4–7.8) | 0.50 |
| Other | 27 (10) | 2.0 (0.7–5.4) | 0.12 |
| Treatment Characteristics | |||
| Concurrent chemo summary | |||
| Full Dose (reference) | 141(52.2) | ||
| Sensitizing | 93 (34.4) | 1.0 (0.5–1.9) | 0.89 |
| No chemo | 36 (13.3) | 0.4 (0.1–1.4) | 0.17 |
| Baseline Frailty Markers | |||
| ECOG PSa | N = 257 | ||
| Median | 1 | 1.7 (1.0–2.9) | 0.07 |
| Range | 0–3 | ||
| CCIa | N = 270 | ||
| Median | 5 | 1.0 (0.9–1.2) | 0.73 |
| Range | 2–16 | ||
| Patient reported weight loss | N = 269 | ||
| No (reference) | 100 (37.2) | ||
| Yes | 169 (62.8) | 1.0 (0.5–1.8) | 0.90 |
| BMI (kg/m2) | N = 270 | ||
| > 20 (reference) | 244 (90.4) | ||
| ≤ 20 | 26 (9.6) | 1.9 (0.8–4.9) | 0.16 |
| Hemoglobin (g/dL) | N = 259 | ||
| > 10 (reference) | 233 (90.0) | ||
| ≤ 10 | 26 (10.0) | 3.3 (1.4–7.9) | 0.01 |
| Creatinine (mg/dL) | N = 258 | ||
| ≤ 1.1 (reference) | 206 (79.8) | ||
| > 1.1 | 52 (20.2) | 1.1 (0.5–2.3) | 0.91 |
| Albuminb (g/dL) | N = 254 | ||
| Median | 3.7 | 3.1 (1.6–5.9) | < 0.01 |
| Range | 2.3–4.8 | ||
a Odds ratio corresponds to 1 point increase in age, ECOG, and CCI
b Odds ratio corresponds to 1 g/dL decrease in albumin
OR odds ratio; ECOG PS Eastern Cooperative Oncology Group performance status; CCI Charlson Comorbidity Index; BMI body mass index