Figure 5.

Infection of HeLa cells with coxsackievirus B3 (CVB3) results in the proteolytic cleavage of Ras GTPase‐activating protein‐binding protein 1 (G3BP1). HeLa cells were infected at a MOI of 20 with CVB3, (mock control sample treated with media alone). At each time‐point, the cells were lysed and the expression of G3BP1 and viral proteins VP1 and 3C^pro were analysed by Western blot. The arrow indicates an accumulation of G3BP1 cleavage product 6 h post infection. Actin was used as a loading control.