Table 2.
Subject | Age at HSCT (year) | Gender | Primary disease |
Conditioning regimen, first HDCT, second HDCT |
Biopsy findings |
Symptom, time after HSCT (month) |
CT findings | Outcome, time after HSCT (month) |
---|---|---|---|---|---|---|---|---|
1 | 2 | F | MBL |
1. CyM 2. BM |
Interstitial fibrous thickening with lymphocytic infiltration |
Dyspnea, chest discomfort 74 |
Subpleural thickening |
Death 84 |
2 | 8 | M | MBL |
1. CT 2. CyM |
Pleural thickening |
Dyspnea 5 |
Interstitial thickening ground glass opacity |
Death 15 |
3 | 1 | F | NBL |
1. CECy 2. TM |
Interstitial fibrosis and inflammatory cell infiltration |
Cough, dyspnea 16 |
Subpleural consolidation, ground glass opacity |
Death 39 |
4 | 3 | F | NBL |
1. CECy 2. TM |
Interstitial fibrosis and inflammatory cell infiltration |
Cough, dyspnea 28 |
Pleural and interstitial thickening ground glass opacity |
Death 46 |
5 | 2 | F | NBL |
1. CECy 2. TM |
Interstitial fibrosis and patch lymphocytic infiltration |
Cough, dyspnea 32 |
Fibrotic change with volume reduction, subpleural ground glass opacity |
Death 62 |
6 | 3 | F | NBL |
1. CECy 2. TM |
Interstitial thickening |
Cough, dyspnea 50 |
Perifissural, subpleural consolidation, uneven aeration |
Alive 63 |
7 | 2 | F | NBL |
1. CECy 2. CEM |
Interstitial fibrosis and lymphocytic infiltration |
Cough, dyspnea 7 |
Interstitial septal thickening, ground glass opacity |
Death 23 |
8 | 2 | F | NBL |
1. CECy 2. TM |
Fibrotic scar |
Dyspnea 74 |
Patchy supleural consolidation, interstitial thickening |
Alive 96 |
BM, Busulfan and melphalan; CECy, carboplatin, etoposide and cyclophosphamide; CEM, carboplatin, etoposide and melphalan; CT, computed tomography; CTE, carboplatin, thiotepa and etoposide; CyM, cyclophosphamide and melphalan; MBL, medulloblastoma; NBL, neuroblastoma; TM, thiotepa and melphalan.