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. 2016 Apr 12;21(6):1068–1074. doi: 10.1111/resp.12787

Table 2.

Clinical features of patients with interstitial lung disease

Subject Age at HSCT (year) Gender Primary disease

Conditioning regimen,

first HDCT,

second HDCT

Biopsy findings

Symptom,

time after HSCT (month)

CT findings Outcome, time after HSCT (month)
1 2 F MBL

1. CyM

2. BM

Interstitial fibrous thickening with lymphocytic infiltration

Dyspnea, chest discomfort

74

Subpleural thickening

Death

84

2 8 M MBL

1. CT

2. CyM

Pleural thickening

Dyspnea

5

Interstitial thickening

ground glass opacity

Death

15

3 1 F NBL

1. CECy

2. TM

Interstitial fibrosis and inflammatory cell infiltration

Cough, dyspnea

16

Subpleural consolidation,

ground glass opacity

Death

39

4 3 F NBL

1. CECy

2. TM

Interstitial fibrosis and inflammatory cell infiltration

Cough, dyspnea

28

Pleural and interstitial thickening

ground glass opacity

Death

46

5 2 F NBL

1. CECy

2. TM

Interstitial fibrosis and patch lymphocytic infiltration

Cough, dyspnea

32

Fibrotic change with volume reduction,

subpleural ground glass opacity

Death

62

6 3 F NBL

1. CECy

2. TM

Interstitial thickening

Cough, dyspnea

50

Perifissural, subpleural consolidation,

uneven aeration

Alive

63

7 2 F NBL

1. CECy

2. CEM

Interstitial fibrosis and lymphocytic infiltration

Cough, dyspnea

7

Interstitial septal thickening,

ground glass opacity

Death

23

8 2 F NBL

1. CECy

2. TM

Fibrotic scar

Dyspnea

74

Patchy supleural consolidation, interstitial thickening

Alive

96

BM, Busulfan and melphalan; CECy, carboplatin, etoposide and cyclophosphamide; CEM, carboplatin, etoposide and melphalan; CT, computed tomography; CTE, carboplatin, thiotepa and etoposide; CyM, cyclophosphamide and melphalan; MBL, medulloblastoma; NBL, neuroblastoma; TM, thiotepa and melphalan.