Table 1.
Outcome studies in SARS
| Study | No. of patients | Virological documentation | Follow up duration | End‐points | Prognostic factors implicated | ||
|---|---|---|---|---|---|---|---|
| ICU admission | Ventilation support | Mortality | |||||
| Lee et al. 3 | 138 | NR | NR | 32(23.2%) | 19 (13.8%) | 3.6% (21‐day) | Age, peak LDH, neutrophil count above normal |
| Booth et al. 4 | 144 | NR | 21 days | 29 (20%) | 20 (14%) | 6.5% (21‐day) | Comorbidity (Diabetes) |
| Wong et al. 5 | 157 | 87.9% | Median 26 days | NR | NR | NR | Age, initial LDH level, low initial CD4, CD8 count |
| Chan et al. 6 | 115 | 89% | Median 62 days | 39 (34%) | 30 (26%) | 10% (21‐day) | Age, comorbidity (Diabetes, heart disease) |
| Peiris et al. 7 | 75 | 93% | 24 days | 24 (32%) | 19 (25%) (ARDS: 20%) | 6.7% (21‐day) | Age, comorbidity (hepatitis B) |
| Tsui et al. 2 | 323 | 89% | <5 weeks | 67 (21%) | 42 (13%) | NR | Age, initial LDH, neutrophil count |
| Lew et al. 8 | 199 | NR | 28 days | 46 (23%) | 39 (19.5%) (ALI/ARDS: 22.6%) | 10.1% (28‐day) | APACHE II score, baseline PaO2/FiO2 ratio |
| Fowler et al. 9 | 196 | NR | 28 days | 38 (19%) | 29 (14.8%) | 6.6% (28‐day) | Age, Diabetes, bilateral lung infiltrates |
ICU, intensive care unit; ALI, acute lung injury; ARDS, acute respiratory distress syndrome; NR, not reported.