Table II.

Parameters and Likelihood of Dose‐Response Models Fitted to Data Sets on Coronavirus Infection

No.	Virus	Host		Beta‐Poisson(BP)				Exponential (EXP)			Better Fit Model**	Unit of Dose
		Species	Age	ln α	ln N 50	Deviance	P fit	ln k	Deviance	P fit
1	rSARS‐CoV	tgMice	?	‐*	‐	‐	‐	5.82	0.97	0.81		PFU
2	MHV‐1	Mice	6 to 8 weeks	1.23	5.71	0.54	0.76	6.15	0.61	0.89	EXP	PFU
p†	SARS‐CoV	Mice	?	6.50	5.64	1.75	0.94	6.01	1.75	0.97	EXP	PFU
3	HCoV‐229E	Humans	18 to 50 years	−0.21	2.38	1.42	0.49	2.92	2.31	0.51	EXP	TCD50
4	MHV‐S	Mice	3 days	‐	‐	‐	‐	6.32	0.56	0.91		PFU
5	MHV‐S	Mice	1 week	‐	‐	‐	‐	8.62	0.56	0.91		PFU
6	MHV‐S	Mice	2 weeks	‐	‐	‐	‐	13.6	0.24	0.97		PFU
7	MHV‐2	Mice	3 weeks	(No death among 5 mice at doses from 7 × 102 to 7 × 104)								PFU
8	MHV‐2	Mice	4 weeks	(No death among 5 mice at doses from 6 × 103 to 6 × 105)								PFU
9	HEV‐67N	Mice	1 week	‐	‐	‐	‐	2.39	0††			PFU
10	HEV‐67N	Mice	4 weeks	‐	‐	‐	‐	7.62	0.62	0.96		PFU
11	HEV‐67N	Mice	8 weeks	‐	‐	‐	‐	7.62	0.62	0.96		PFU
12	HEV‐67N	Rats	1 week	‐	‐	‐	‐	3.08	0††			PFU
13	HEV‐67N	Rats	4 weeks	‐	‐	‐	‐	8.66	0.54	0.76		PFU
14	HEV‐67N	Rats	8 weeks	−1.04	7.42	1.97	0.16	9.34	6.36	0.04	BP	PFU
15	IBVA‐5968	Chicks	9 weeks	−5.11	109	2.93	0.57	11.4	26.6	<0.01	BP	CD50

*Beta‐Poisson model was not fitted to data sets including less than two dose points corresponding to other than 0 or 100% response.

**Beta‐Poisson model was employed if it provided a significant improvement of fit (p > 0.05) rather than exponential model.

^†Data set p pooled data sets 1 and 2.

^††Zero deviance means that all data were on the model.