Table 1.
Decision procedure for the dose‐tapering regimen
| Inclusion (V1; day 0) | Day 28 (±3 days) | Day 56 (±3 days) |
|---|---|---|
|
7 mg/kg daily, all cats |
No response: score 3 or 4, drop out | Not applicable |
| Insufficient response: score 2, 7 mg/kg daily | No response: score 3 or 4, drop out | |
| Insufficient response: score 2, administer 7 mg/kg daily | ||
| Good or excellent response: score 0 or 1, administer 7 mg/kg every other day | ||
| Good or excellent response: score 0 or 1, 7 mg/kg every other day | No response: score 3 or 4, return to 7 mg/kg daily | |
| Insufficient response: score 2, administer 7 mg/kg every other day | ||
| Good or excellent response: score 0 or 1, administer 7 mg/kg twice a week |
The clinical improvement was scored as described in the Materials and methods (section ‘Assessment of the clinical response’).
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