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Immunohistochemistry analysis for COX-2 expression evaluation. Saline (A); 5-FU (B); TRX-100 (C); CLX (D); TRX and CLX (E); % immunolabelled for COX-2 (F). Values were expressed as mean ± SEM. For statistical analysis, one-way ANOVA followed by Tukey’s test was used, where # p < 0.05 vs. saline group, * p < 0.05 vs. group 5-FU.
