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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Food Chem Toxicol. 2020 Mar 9;139:111254. doi: 10.1016/j.fct.2020.111254

Table 4 –

Serum biochemistry.

Dose
Water Low Medium High BB
Total protein (g/dL) 6.01 ± 0.21 6.03 ± 0.24 6.03 ± 0.21 5.99 ± 0.17 5.99 ± 0.17
Albumin (g/dL) 3.39 ± 0.14 3.39 ± 0.18 3.42 ± 0.14 3.42 ± 0.16 3.40 ± 0.15
Globulin (g/dL) 2.62 ± 0.10 2.64 ± 0.11 2.61 ± 0.11 2.57 ± 0.07 2.59 ± 0.11
A/G ratio 1.29 ± 0.06 1.29 ± 0.09 1.32 ± 0.04 1.32 ± 0.06 1.32 ± 0.10
BUN (mg/dL) 14.9 ± 2.42 17.6 ± 3.10 16.8 ± 2.49 14.8 ± 1.32 16.3 ± 3.50
Creatinine (mg/dL) 0.67 ± 0.15 0.69 ± 0.09 0.74 ± 0.09 0.70 ± 0.12 0.68 ± 0.10
ALKP (U/L) 123 ± 30.7 112 ± 18.0 111 ± 25.1 117 ± 19.9 114 ± 15.7
ALT (U/L) 50.3 ± 8.3 48.9 ± 9.1 45.7 ± 7.7 53.8 ± 10.7 44.0 ± 5.9
Total bilirubin (mg/dL) 0.12 ± 0.04 0.17 ± 0.05 0.15 ± 0.05 0.14 ± 0.05 0.17 ± 0.07
Amylase (U/L) 1662 ± 318 1517 ± 333 1614 ± 393 1702 ± 304 1673 ± 362
Lipase (U/L) 97.0 ± 23.3 100 ± 35.8 105 ± 27.2 101 ± 15.9 120 ± 35.0
Cholesterol (mg/dL) 135 ± 10.3 128 ± 11.2 123 ± 14.8 118 ± 8.9* 131 ± 20.0
Calcium (mg/dL) 11.6 ± 0.20 11.6 ± 0.30 11.5 ± 0.35 11.6 ± 0.13 11.5 ± 0.26
Chloride (mmol/L) 99.4 ± 1.2 99 ± 1.3 98.6 ± 1.2 97.3 ± 0.9* 99.8 ± 1.6
Phosphorus (mg/dL) 7.53 ± 0.61 7.96 ± 0.83 7.52 ± 0.81 7.40 ± 0.52 7.41 ± 0.35
Potassium (mmol/L) 7.02 ± 0.80 7.27 ± 0.89 7.36 ± 0.47 7.06 ± 0.72 7.10 ± 0.83
Sodium (mmol/L) 141 ± 1.5 141 ± 1.0 142 ± 1.1 141 ± 0.9 141 ± 0.8
Anion gap (mmol/L) 16.1 ± 2.40 16.2 ± 2.41 16.6 ± 1.65 17.4 ± 2.17 16.5 ± 2.80
CO2 (mmol/L) 32.7 ± 1.70 33.2 ± 1.62 33.8 ± 2.28 33.2 ± 1.69 32.0 ± 3.91

Values are mean ± SD for 9–10 animals per group.

BB = whole freeze-dried blueberries; A/G = Albumin:Globulin ratio; BUN = Blood Urea Nitrogen; ALKP = Alkaline Phosphatase; ALT = Alanine Transaminase; CO2 = Carbon Dioxide.

*

Significantly different from water control (p<0.05).