Table 2.
Time‐of‐addition assessment for NHC with enteroviruses.
|
Experiment Scheme |
Supposed Target |
Addition of components |
Virus Yield (logTCID50/mL) |
|||
|---|---|---|---|---|---|---|
|
‐1 – 0 h |
0 – 1 h |
1 – 7 h |
EVA71 |
PV1 |
||
|
A |
Control |
DMSO |
DMSO + virus |
DMSO |
4.5±0.18 |
4.0±0.53 |
|
B |
Cell |
NHC |
DMSO + virus |
DMSO |
4.13±0.18 |
3.44±0.09 |
|
C |
Virion |
DMSO |
NHC + virus |
DMSO |
4.19±0.27 |
3.63±0.35 |
|
D |
After entry |
DMSO |
DMSO + virus |
NHC |
2.5±0.01 |
1.44±0.09 |
|
E |
Cell & after entry |
NHC |
DMSO + virus |
NHC |
2.5±0.01 |
1.13±0.53 |
|
F |
Virion & after entry |
DMSO |
NHC + virus |
NHC |
2.75±0.35 |
1.75±0.35 |
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