Table 1.

Characteristics of FFP and current dried plasma products

Criteria	FFP	Existing dried plasma products14, 15, 17
Efficacy	All coagulation factors within normal range. Unit to unit variability based on variability among normal donors.	Factor activity within normal range for nearly all factors. There are decrements in levels of selected factors as a result of drying and pathogen reduction procedures (varies among products). Pooled products (FLYP, Bioplasma FDP), have reduced unit to unit variability compared to FFP.
Blood type	ABO	ABO (LyoPlas N‐w) or Universal (FLYP and Bioplasma FDP)
Preparation/reconstitution time	30–40 min	<10 min
Preparation/reconstitution requirements	Water bath or other FDA‐approved thawing device	None
Storage temperature	≤−18ºC	Refrigerated or up to room temperature (25°C)
Shelf‐life	12 months	15–24 months
Product packaging	Bag (200 to 250 mL)	Bottle (50 or 200 mL)