Table 3.


 Univariable risks for respiratory viral infection (RVI)

	Univariable hazard ratios for time to RVI
Risk factor	Number in analysis	Hazard ratio (95% CI)	P‐value
Age at transplant in years (quintiles)
16.4–21	115	Reference	<0.01
14–16.4	113	0.85 (0.29, 2.5)
11.4–14	116	2.5 (1.02, 6.0)
5.5–11.4	113	3.2 (1.3, 7.5)
0–5.4	117	4.7 (2.1, 10.8)
Year of transplant (quintiles)
2002–2005	122	Reference	0.063
1985–1992	88	1.1 (0.41, 2.8)
1993–1996	142	1.9 (0.91, 4.1)
1997–1998	92	2.4 (1.07, 5.2)
1999–2001	132	2.5 (1.2, 5.2)
No induction therapy	532	1.9 (1.2, 3.1)	0.012
Home‐going regimen: cyclosporine	576	1.8 (1.00, 3.1)	0.049
Diagnosis other than cystic fibrosis	575	3.2 (2.0, 5.3)	<0.001
Transplant type
Heart/lung	134	Reference	0.073
Single	14	1.1 (0.14, 8.7)
Living donor	27	2.5 (0.76, 8.0)
Bilateral cadaveric	400	2.5 (1.2, 4.9)
CMV before RVI	576	1.2 (0.60, 2.3)	0.66
Any rejection before RVI	576	0.78 (0.47, 1.3)	0.34
Two rejections before RVI	576	0.67 (0.38, 1.2)	0.17
A2 rejection before RVI	576	1.06 (0.63, 1.8)	0.83
Two A2 rejections before RVI	576	0.90 (0.44, 1.9)	0.78
Two treated rejections before RVI	576	0.77 (0.40, 1.5)	0.43
BOS before RVI	576	1.7 (0.50, 5.5)	0.69

CI, confidence interval; CMV, cytomegalovirus; A2, grade of rejection; BOS, bronchiolitis obliterans syndrome.