Table 3.

Case studies of potential antiviral agents against the SARS-CoV-2.

Antiviral agent	Target	Molecular structure	Antiviral activity (μmol/L)	Score	Rank	Ref.
Remdesivir-active form	RdRp		EC50 = 0.77	−11.37	3/42	34
Favipiravir-active form	RdRp		EC50 = 61.88	−10.74	2/42	34,37,38
Ribavirin-active form	RdRp		EC50 = 109.50	−10.39	2/42	34,38,39
Penciclovir-active form	RdRp		EC50 = 95.96	−8.82	5/42	34,40
N3 compound	3CLpro		EC50 = 16.77	−9.45	4/42	41
Teriflunomide	DHODH		IC50 = 0.31	−9.26	2/42	42