Table II.
Correlation of CDK5 with cytogenetic abnormalities and immunophenotypes in MM.
| MM | n CD | K5+ (n) | CDK5− (n) | P-value |
|---|---|---|---|---|
| 17p13 deletion | 0.914 | |||
| Positive | 5 | 3 | 2 | |
| Negative | 60 | 28 | 32 | |
| 1q21amplification | 0.730 | |||
| Positive | 35 | 16 | 19 | |
| Negative | 30 | 15 | 15 | |
| IgH rearrangement | 0.204 | |||
| Positive | 15 | 5 | 10 | |
| Negative | 50 | 26 | 24 | |
| 13q14 deletion | 0.179 | |||
| Positive | 35 | 14 | 21 | |
| Negative | 30 | 17 | 13 | |
| CD117 | 0.172 | |||
| Positive | 16 | 10 | 6 | |
| Negative | 49 | 21 | 28 | |
| CD20 | 0.385 | |||
| Positive | 9 | 6 | 3 | |
| Negative | 56 | 25 | 31 | |
| CD56 | 0.428 | |||
| Positive | 43 | 19 | 24 | |
| Negative | 22 | 12 | 10 | |
| CD81 | 0.789 | |||
| Positive | 43 | 20 | 23 | |
| Negative | 22 | 11 | 11 | |
| CD45 | 0.818 | |||
| Positive | 24 | 11 | 13 | |
| Negative | 41 | 20 | 21 | |
| CD27 | 0.180 | |||
| Positive | 18 | 11 | 7 | |
| Negative | 47 | 20 | 27 | |
| CD28 | 0.881 | |||
| Positive | 9 | 5 | 4 | |
| Negative | 56 | 26 | 30 | |
| CD33 | 0.456 | |||
| Positive | 13 | 5 | 8 | |
| Negative | 52 | 26 | 26 |
MM, multiple myeloma; CDK, cyclin dependent kinase; CD, cluster of differentiation; Ig, immunoglobulin.