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. 2020 Mar 20;45(6):1685–1696. doi: 10.3892/ijmm.2020.4547

Figure 2.

Figure 2

Silencing of SNHG14 represses the proliferation, migration and invasion, and facilitates the apoptosis of Y79 and Weri-RB-1 cells. (A) Y79 and Weri-RB-1 cells were transfected with either si-SNHG14 or si-NC. Expression of SNHG14 was analyzed at 48 h post-transfection. **P<0.01 vs. the si-NC group. (B) Proliferation of SNHG14-deficient Y79 and Weri-RB-1 cells was quantitated in the Cell Counting Kit-8 assay. *P<0.05 vs. the si-NC group. (C) Flow cytometry was utilized to measure the apoptotic rates of Y79 and Weri-RB-1 cells following either si-SNHG14 or si-NC transfection. **P<0.01 vs. the si-NC group. (D and E) The levels of migration and invasion in the SNHG14 knockdown Y79 and Weri-RB-1 cells were assessed using (D) Transwell migration and (E) invasion assays. Magnification, ×200 magnification. **P<0.01 vs. the si-NC group. SNHG14, small nucleolar RNA host gene 14; si, small interfering RNA; NC, negative control; FITC, fluorescein isothiocyanate.