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. Author manuscript; available in PMC: 2021 Apr 15.
Published in final edited form as: Alcohol Clin Exp Res. 2020 Apr 15;44(4):939–959. doi: 10.1111/acer.14313

Table 5.

Proximal Maternal Risk Factors for FASD: Alcohol and Drug Use a Southeastern County

Children with
FASD
(n=47)
Randomly-
Selected
Control
Children
(n=251)
χ2
or
t-test
p-value
Mean (SD) Mean (SD)
Alcohol Use – Before and During Pregnancy
Drank before pregnancy (% Yes) 83.0 49.6 17.784 <.001**
# of drinks consumed on usual drinking day before pregnancy1 4.3 (2.1) 2.6 (2.8) 3.314 .001**
Mdn = 4.0 Mdn = 2.0 --
Usual frequency – before pregnancy1
 Everyday or almost everyday 13.2 7.4
 3-4 times per week 10.5 5.8
 1-2 times per week 47.4 24.0
 3 times per month 18.4 16.5
 1 time per month or less 10.5 46.3 16.865 .002**
Days drank more than usual – before pregnancy1 (% Yes) 22.7 15.8 1.284 .257
Drank in 1st trimester (% Yes) 24.4 4.4 22.080 <.001A,**
# of drinks on usual drinking day1 -1st 3.4 (2.9) 5.2 (6.7) −0.718 .483
Usual frequency1 – 1st
 Everyday or almost everyday 18.2 10.0
 3-4 times per week 18.2 10.0
 1-2 times per week 27.3 10.0
 2-3 times per month 0.0 0.0
 1 time per month or less 36.4 70.0 2.443 .486
Drank in 2nd trimester (% Yes) 17.8 1.6 25458 <.001A,**
# of drinks on usual drinking day1 -2nd 1.7 (1.0) 6.3 (9.2) −0.872 .474
Usual frequency1 – 2nd
 Everyday or almost everyday 25.0 33.3
 3-4 times per week 12.5 0.0
 1-2 times per week 25.0 33.3
 2-3 times per month 0.0 0.0
 1 time per month or less 37.5 33.3 .497 .920
Drank in 3rd trimester (% Yes) 17.0 3.2 14.660 <.001A,**
# of drinks on usual drinking day1 - 3rd 1.1 (0.4) 2.4 (3.5) −0.922 .373
Usual frequency1 – 3rd
 Everyday or almost everyday 0.0 12.5
 3-4 times per week 0.0 12.5
 1-2 times per week 0.0 0.0
 2-3 times per month 0.0 0.0
 1 time per month or less 100.0 75.0 3.013 .556
Alcohol Use - Current
Drink in past 30 days (% Yes) 59.1 52.7 .617 .432
Binge 5+ in past month (% Yes) 14.0 10.3 .494 .482
Why usually drink: because others drink 25.0 16.3 1.967 .161
Why usually drink: to feel less anxious 11.4 7.3 .837 .360
Recovering drinker (% Yes) 0.0 1.0 .362 .547
Other Drug Use
Used tobacco – during pregnancy (% Yes) 38.3 13.2 17.521 <.001**
Used any drugs in pregnancy (% Yes) 17.0 4.0 11.562 .001A,**
Abused prescription drugs – in pregnancy 8.5 1.6 7.125 .024A,*
Used marijuana – during pregnancy (% Yes) 14.9 2.8 12.663 .002A,**
Used marijuana & alcohol – during pregnancy (% Yes) 14.9 0.4 30.660 <.001A**
Used cocaine - during pregnancy (% Yes) 8.9 0.8 12.346 .006A,*
Used tobacco
 Yes, within last 30 days 40.4 18.5
 Yes, in lifetime 25.5 32.1
 Never 34.0 49.4 13.658 .001**
Used any drug in lifetime (% Yes) 70.2 42.3 12.331 <.001**
Used marijuana – in lifetime (% Yes) 70.2 41.7 12.913 <.001**
Used methamphetamine – in lifetime (% Yes) 6.7 2.0 3.056 .110
Used heroin – in lifetime (% Yes) 8.9 1.2 9.531 .012A,*
Used club drugs – in lifetime (% Yes) 30.4 7.8 19.813 <.001A,**
Used crack/cocaine – in lifetime (% Yes) 19.6 5.3 11.422 .003A,**
Abused pain killers – in lifetime (% Yes) 17.0 5.6 7.409 .013*
1

Among women who drank in that specific time period.

A

Fisher’s Exact Test

*

Significant at <0.05

**

Bonferroni-adjusted significant levels: alcohol use -before and during pregnancy = 0.004; alcohol use – current = 0.01; other drug use = 0.004.