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. Author manuscript; available in PMC: 2021 Apr 15.
Published in final edited form as: Alcohol Clin Exp Res. 2020 Apr 15;44(4):939–959. doi: 10.1111/acer.14313

Table 6.

Distal Maternal Risk Factors for FASD: Physical, Demographic, and Childbearing Variables in a Southeastern County

Children with
FASD
(n=47)
Randomly-
Selected
Control
Children
(n=251)
χ2
or
t-test
p-value
Mean (SD) Mean (SD)
Physical
Age at pregnancy (yrs) 27.6 (5.8) 28.5 (5.8) 0.675 .335
Height at interview (cm) 161.7 (6.1) 163.2 (8.0) −1.117 .240
Weight at interview (kg) 73.9 (17.2) 78.2 (20.0) −1.304 .193
Body Mass Index (BMI) 28.2 (6.3) 29.3 (7.0) −0.936 .350
Head circumference 55.2 (1.9) 55.6 (2.4) −1.072 .284
Health indicators
Weight before pregnancy (in kg) 65.2 (17.5) 67.3 (15.8) 0.763 .401
Asthma – in lifetime (% Yes) 22.2 12.1 3.313 .069
Stomach ulcers – in lifetime (% Yes) 4.5 3.6 0.083 .675A
Neurological conditions/ epilepsy - lifetime 15.6 5.6 5.622 .027A*
Liver problems / hepatitis – in lifetime 11.1 2.4 7.915 .016A*
Depression – in lifetime (% Yes) 70.2 41.9 12.702 <.001**
Childbearing
Gravidity 3.7 (2.8) 3.2 (1.7) 1.114 .270
Parity 2.7 (1.1) 2.6 (1.2) 0.419 .676
Miscarriages 0.9 (2.3) 0.5 (1.1) 1.161 .251
Abortions 0.1 (0.5) 0.1 (0.3) 0.666 .508
Stillbirths 0.0 (0.2) 0.0 (0.1) 0.940 .348
Birth order of index child 2.0 (1.1) 2.0 (1.2) 0.408 .880
Week of pregnancy recognition 7.7 (5.6) 5.7 (3.1) 2.355 .022
Prenatal Care
Once knew pregnant, take vitamins (% Yes) 93.3 95.9 0.603 .432
# of times seen by healthcare provider
 Never 2.3 0.4
 1-5 times 0.0 1.2
 More than 5 times 97.7 98.4 2.441 .323
When first seen by healthcare provider
 1st trimester 84.4 93.6
 2nd trimester 11.1 4.8
 3rd trimester 2.2 0.8
 Delivery only 2.2 0.8 4.500 .183
Other health problems - during pregnancy 30.4 25.1 0.574 .466
Accidents/injury – during pregnancy (% Yes) 8.7 10.8 0.190 .798A
Postpartum depression (% Yes) 27.3 20.2 1.101 .319
Postnatal Variables
Child’s Birth weight (grams) 2970 (864) 3225 (596) −1.921 .060
Estimated gestation age at birth (in weeks) 37.7 (3.8) 38.7 (2.2) −1.735 .089
COI had problem(s) at birth (% Yes) 59.6 50.0 1.450 .266A
Breastfed (% Yes) 55.3 76.0 8.531 .005*
Duration of breastfeeding (in months)1 5.5 (6.0) 7.6 (7.2) −1.292 .198
Supplement with formula1 76.0 72.0 0.181 .814
Consumed alcohol in breastfeeding period 8.3 13.2 0.461 .746
Pump and dump (%Yes)1 among mothers who breastfed 20.0 28.0 .292 .723A
Pump and dump (% Yes)2 among mothers who drank during period of breastfeeding 100.0 79.2 0.516 1.00A
Age of biological father (in years) 28.7 (7.0) 30.4 (6.4) −1.635 .103
Child lives with biological mother (% Yes) 76.6 93.6 13.749 .001A*
Child lives with:
 Foster/Adopted/Relative 9.5 4.0
 Biological mother 26.2 19.0
 Biological father 4.8 1.6
 Biological mother and father 59.5 75.3 8.957 .023A**
Partner ever had a drinking problem
 Never 75.6 84.1
 In the past, but not currently 14.6 8.4
 Currently 0.0 1.3
 Both past and currently 9.8 6.3 2.923 .404
Years of Education completed 13.5 (2.8) 13.8 (3.4) −0.578 .561
Household yearly income - during pregnancy 45549 (42587) 58256 (40656) −1.839 .067
Household yearly income – at interview 51125 (41147) 67398 (52400) −1.942 .053
Marital Status – Current
 Married 52.2 68.5
 Divorced/Widowed/Separated/Single 30.4 17.3
 Living with partner 17.4 14.1 5.294 .073
Marital Status – During Pregnancy
 Married 40.4 68.4
 Divorced/Widowed/Separated/Single 17.0 7.6
 Living with partner 42.6 24.0 13.758 .002A**
Spirituality: none [0] to high [10]1 5.6 (2.2) 6.9 (2.3) −3.598 <.001**
1

Among women who breastfed.

2

Among women who breastfed and consumed alcohol in the breastfeeding period.

3

Among women who reported drinking in the specific time period.

4

Pump and dump is the colloquial name for expressing breastmilk after drinking alcohol and disposing of it.

A

Fisher’s Exact Test

*

Significant at 0.05

**

Significant at the Bonferroni-adjusted level: physical = 0.01; health indicators = 0.01; childbearing = 0.007; prenatal care = 0.001; postnatal = 0.004.