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. Author manuscript; available in PMC: 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr 8;580(7803):402–408. doi: 10.1038/s41586-020-2188-x

Extended Data Fig. 7 |. Investigation of tissue-preferential expression data.

Extended Data Fig. 7 |

a, Examples of genes displaying different levels of tissue-preferential (TiP) expression across the GTEx tissue panel (left), with boxplots showing median, interquartile range (IQR), and 1.5 × IQR (with outliers), n = 90–779 samples per tissue. Equation to calculate tissue-preferential expression for every gene-tissue pair and the maximum TiP value for every gene (middle). Number of genes showing tissue-preferential expression for increasing tissue-preferential expression cutoffs (right). b, Relative number of TiP genes for every tissue for increasing tissue-preferential expression cutoffs. c-d, Differences in number of TiP genes upon removal of testis prior to TiP value calculation per tissue (TiP value cutoff = 2) (c) and in total for increasing tissue-preferential expression cutoffs (d). e, Number of TiP genes and number of TiP genes that are also exclusively expressed in one tissue (sglTis: single tissue) for increasing tissue-preferential expression cutoffs.