TABLE 3.
Nonadherence to elements of the post lung transplantation regimen at the end of the RCT and at long-term follow-up assessment by study group assignment, Pocket PATH vs usual care
| 12-month assessment | Long-term follow-up assessment | Comparisons over time in total cohort | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Nonadherence characteristics assessed | Total (N = 101) | Pocket PATH (n = 44) | Usual care (n = 57) | Pa | Total (N = 105) | Pocket PATH (N = 47) | Usual care (N = 58) | Pb | Did nonadherence level change from 12 mo to follow-up?c | Was nonadherence at follow-up associated with nonadherence at 12 mo (end of trial)?d |
| Total number of nonadherent elements, M (SD) | 2.0 (1.4) | 1.6 (1.2) | 2.3 (1.4) | 0.022 | 2.9 (1.5) | 2.7 (1.5) | 3.1 (1.5) | 0.218 | <0.001 | <0.001 |
| Specific areas of the regimen | ||||||||||
| Primary immunosuppressant medication (missed >1 per mo), % (n) | 7.9 (8) | 4.5 (2) | 10.5(6) | 0.460b | 13.3(14) | 6.4 (3) | 19.0(11) | 0.059 | 0.424 | 0.020 |
| Nonimmunosuppressant medications (missed >1 per mo), % (n) | 14.9(15) | 9.1 (4) | 19.3(11) | 0.153 | 22.9 (24) | 17.0(8) | 27.6(16) | 0.200 | 0.230 | 0.064 |
| Clinic appointments (missed any visits in past y), % (n) | 1.0(1) | 0.0 (0) | 1.8(1) | 1.000b | 31.4 (33) | 38.3(18) | 25.9(15) | 0.172 | <0.001 | 0.140 |
| Spirometry (<several times per wk in first y posttransplant; <weekly at follow-up), % (n) | 64.4 (65) | 54.5 (24) | 71.9 (40) | 0.070 | 81.0(85) | 80.9 (38) | 81.0 (47) | 0.981 | 0.017 | 0.650 |
| Monitoring blood pressure (<several times per wk in first y posttransplant; <weekly at follow-up), % (n) | 64.4 (65) | 50.0 (22) | 75.4 (43) | 0.008 | 64.8 (68) | 59.6 (28) | 69.0 (40) | 0.317 | 1.000 | 0.012 |
| Diet (went off diet > occasionally), % (n) | 17.8(18) | 18.2(8) | 17.5(10) | 0.934 | 22.9 (24) | 17.0(8) | 27.6(16) | 0.200 | 0.424 | 0.016 |
| Exercise (< once per wk), % (n) | 27.7 (28) | 25.0(11) | 29.8(17) | 0.591 | 57.1 (60) | 48.9 (23) | 63.8 (37) | 0.126 | <0.001 | 0.008 |
| Tobacco use (any), % (n) | 1.0(1) | 2.3(1) | 0.0 (0) | 0.436b | 3.8 (4) | 6.4 (3) | 1.7(1) | 0.323b | 0.250 | 0.018 |
Comparing the 2 intervention groups at the last (12-mo) assessment in the original RCT.
Comparing the 2 intervention groups at the long-term follow-up.
Paired t test to compare means and McNemar test to compare proportions. Comparisons include the 101 patients with both the 12-mo and long-term follow assessments.
t test associated with correlation coefficient to compare total number of nonadherent elements and χ2 test to compare proportions. Comparisons include the 101 patients with both the 12-month and long-term follow-up assessments.
Pocket PATH, pocket personal assistant for tracking health; RCT, randomized controlled trial; SD, standard deviation.