TABLE 4.
Generalized linear mixed model predicting CC-0 resection and major in-hospital postoperative complications across all CRS-HIPEC procedures
| Variable | p value | Odds ratioa | 95% CI | |
|---|---|---|---|---|
| Predictors of CC-0 resection | ||||
| Primary tumor diagnosis (referent: appendix cancer) | Colorectal cancer | 0.008 | 2.95 | 0.9, 9.3 |
| Mesothelioma | 0.21 | 0.06, 75.8 | ||
| Ovarian cancer | 1.74 | 0.1, 28.6 | ||
| PCI (per one unit increase) | <0.0001 | 0.87 | 0.8, 0.9 | |
| Predictors of major in-hospital postoperative complications (CDC grades 3–4) | ||||
| CC-score (referent: CC-0) | CC-1 | 0.004 | 2.77 | 1.5, 5.0 |
| CC-2 | 3.59 | 1.3, 10.2 | ||
| CC-3 | 2.0 | 0.2, 23.8 | ||
CRS-HIPEC cytoreductive surgery-hyperthermic intraperitoneal chemoperfusion; CC completion of cytoreduction score; PCI peritoneal cancer index; CDC Clavien-Dindo classification
Assuming that PCI is at its mean value (16.05)