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Cytotoxicity of YPM F and G against Selected Human Cancer Cell Lines.a
| cell lines | cancer type | IC50 (μM) Mitomycin | IC50 (nM) |
||
|---|---|---|---|---|---|
| YPM A (1) | YPM F (6) | YPM G (7) | |||
| CaCo2 | colon | 5.80 ± 0.80 | 3.40 ± 0.40 | 3.16 ± 0.07 | 55.20 ± 6.70 |
| Jurkat | lymphoma | 0.43 ± 0.13 | 0.24 ± 0.07 | 0.17 ± 0.02 | 0.62 ± 0.46 |
| A549 | lung | 0.27 ± 0.06 | 0.02 ± 0.02 | 0.24 ± 0.09 | 3.41± 0.49 |
| SKBR-3 | breast | 1.00 ± 0.20 | 0.86 ± 0.07 | 2.56 ± 0.96 | 24.20 ± 6.00 |
The IC50s were determined by computerized curve fitting using GraphPad Prism.
