Table 2.
Univariate and multivariate analysis for OS in trainning cohort.
| Cetegory | Univariate analysis | Multivariate analysis | |
|---|---|---|---|
| P | Hazard ratio (95% CI) | P | |
| Age (y) | <0.001 | ||
| <51 | Reference | ||
| 51–58 | 1.272 (1.029–1.572) | 0.026 | |
| >58 | 2.032 (1.678–2.462) | <0.001 | |
| Race | 0.003 | ||
| White | Reference | ||
| Black | 1.278 (1.045–1.563) | 0.017 | |
| Other* | 1.187 (0.918–1.534) | 0.190 | |
| Year at diagnosis | 0.896 | ||
| 2004–2009 | |||
| 2010–2015 | |||
| Grade** | <0.001 | ||
| Low | Reference | ||
| High | 2.329 (1.796–3.021) | <0.001 | |
| Stage | <0.001 | ||
| I | Reference | ||
| II | 2.242 (1.836–3.168) | <0.001 | |
| III | 3.759 (2.878–4.911) | <0.001 | |
| IV | 4.539 (3.690–5.585) | <0.001 | |
| Tumor size (mm) | <0.001 | ||
| <70 | Reference | ||
| 70–140 | 1.376 (1.107–1.709) | 0.004 | |
| >140 | 2.029 (1.606–2.564) | <0.001 | |
| Lymphadenectomy | 0.254 | ||
| Yes | |||
| No | |||
| Surgery type | <0.001 | ||
| Hysterectomy** | Reference | ||
| Pelvic exenteration | 0.695 (0.387–1.247) | 0.222 | |
| No surgery | 2.439 (1.753–3.393) | <0.001 | |
| Radiotherapy | 0.068 | ||
| Yes | |||
| No | |||
| Chemotherapy | <0.001 | ||
| Yes | Reference | ||
| No | 1.280 (1.074–1.526) | 0.005 | |
CI – confidence interval.
*
American Indian/Alaskan Native, Asian/Pacific Islander;
**
Low: Grade I (well differentiated) and Grade II (moderately differentiated); High: Grade III (poorly differentiated) and Grade IV (undifferentiated anaplastic);
***
Total/simple/pan/radical hysterectomy with or without removal of adnexa.