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. 2020 Mar 20;56(6):1455–1467. doi: 10.3892/ijo.2020.5023

Figure 4.

Figure 4

ZEB1-AS1 promotes tumor metastasis and growth in vivo. (A) Number of mice with distant metastasis. (B) Quantification of metastatic foci per section in the liver and lung of individual mice following the injection of HuCCT1 cells with ZEB1-AS1 knockdown or control cells. Representative images are shown. (C) Quantification of metastatic foci per section in the liver and lung of individual mice following the injection of RBE cells with ZEB1-AS1 overexpression or control cells. Representative images are shown. (D) Quantification of tumor volume and tumor weight of individual mice following the injection of HuCCT1 cells with ZEB1-AS1 knockdown or control cells. Representative images are shown. (E) Quantification of tumor volume and tumor weight of individual mice following the injection of RBE cells with ZEB1-AS1 overexpression or control cells. Representative images are shown. Scale bars, 20 µm (B and C), and 1 cm (D and E). *P<0.05. ZEB1-AS1, lncRNA ZEB1 antisense 1; IHCC, intrahepatic cholangiocarcinoma.