Table II.
Mutational status and mutation location of all 70 patients with GIST from the Slovenian Cancer Registry.
| Mutation genotype | Number of GISTs |
|---|---|
| KIT/PDGFRA-mutant GIST | 62 |
| KIT (exon 9) | 6 |
| KIT (exon 11) | 52 |
| KIT (exon 13) | 5a |
| KIT (exon 17) | 3b |
| PDGFRA (exon 12) | 0 |
| PDGFRA (exon 14) | 1c |
| PDGFRA (exon 18) | 1 |
| Wild-typed GIST | 8 |
a
Two GISTs with primary mutation and three GISTs with secondary mutation.
b
Three GISTs with secondary mutation.
c
One GIST with two primary mutations.
d
Wild-type for KIT, PDGFRA, BRAF, KRAS, NRAS, PIK3CA and AKT1. GIST, gastrointestinal tumour.