Table 2.

Measurements during incremental cardiopulmonary exercise testing

Variables	Patients (N=30)	Controls (N=15)
Peak exercise
$\stackrel{.}{\text{V}}$O2, mL/min (% pred)	1088±277 (75±13)	1595±550 (110±19)*
$\stackrel{.}{\text{V}}$O2, mL/Kg/ min	14.6±2.6	23.3±4.5*
$\stackrel{.}{\text{V}}$CO2, mL/min	1138±334	1985±707*
$\stackrel{.}{\text{V}}$E L/min	46.4±14.7	64.6±25.7*
VT, L	1.02±0.24	1.82±0.47*
f breaths/ min	46±11	34±7*
$\stackrel{.}{\text{V}}$E/MW	0.76±0.15	0.59±0.13*
Δ$\stackrel{.}{\text{V}}$E/Δ$\stackrel{.}{\text{V}}$CO2	38.5±9.8	27.8±3.1*
IC, L (% pred)	1.40±0.27 (55±13)	2.61±0.62 (95±13)*
ΔIC, L	0.11 (-0.6-0.4)	0.19 (-0.08-0.5)
HR, beats/min (% pred)	123±20 (76±11)	144±12 (103±28)*
O2 pulse, mL/beats	8.8±2.1	11.1±3.8
Δ$\stackrel{.}{\text{V}}$O2/Δwork, mL/min/watts	9.7±3.5	9.4±1.7
Peak workload, watts (%pred)	49±18 (51±18)	109±35 (106±18)*
SpO2, %	88±7	98±1*
ΔSpO2, %	-8.2±5.3	0.2±1.2*
Borg dyspnoea score	5.9 (1-10)	3.9 (1-10)*
Dyspnoea/$\stackrel{.}{\text{V}}$E, Borg/L/min	0.14 (0.01-0.30)	0.05 (0.01-0.20)*
Borg leg effort score	6.3 (1-10)	5.9 (1-10)
Leg effort/$\stackrel{.}{\text{V}}$CO2, Borg/L/min	5.5 (1.9-12.7)	2.8 (0.3-7.3)*
Anaerobic threshold
$\stackrel{.}{\text{V}}$O2, mL/min (% predicted)	771±173 (53±6)	1083±417 (74±19)*

Data presented as means ± SÇ or median (range).

Definition of abbreviations: $\stackrel{.}{\text{V}}$O₂: oxygen uptake; %pred: % of predicted $\stackrel{.}{\text{V}}$CO₂: carbon dioxide output; $\stackrel{.}{\text{V}}$E: minute ventilation; VT: tidal volume; y=breathing frequency; MMV: maximum voluntary ventilation; IC: inspiratory capacity; ΔI& IC change from rest; HR: heart rate; SpO2: oxyhemoglobin saturation by pulse oximetry. *P<0.05