Table 51-21.
Case-Control Analysis of Risk Factors for Bacteremia or Contaminated Intravenous Fluid with Pseudomonas Pickettii
| Cases (n =9) | Controls* (n =19) | P Value | |
|---|---|---|---|
| Age, Mean | 50 yr | 46 yr | NS† |
| Duration of Surgery, Mean | 4.0 hr | 3.7 hr | NS |
| Type of Surgery | |||
| Cardiovascular | 5 (55) | 3 (16) | NS |
| General | 4 (45) | 16 (84) | |
| Intravenous Fluids | |||
| Lactated Ringer's | 8 (89) | 11 (58) | NS |
| Dextrose in lactate | 5 (55) | 14 (74) | NS |
| Saline 0.9% | 6 (67) | 4 (21) | NS |
| Blood products | 7 (78) | 4 (21) | NS |
| Albumin, fresh frozen plasma | 4 (44) | 2 (10) | NS |
| Intraoperative Intravenous Medications | |||
| Pentothal | 4 (45) | 13 (68) | NS |
| Lidocaine | 5 (55) | 5 (26) | NS |
| Pancuronium | 5 (55) | 4 (21) | NS |
| Heparin | 5 (55) | 0 (0) | <.001 |
| Cefazolin | 9 (100) | 10 (53) | NS |
| Fentanyl | 9 (100) | 9 (47) | .05 |
| Volume of intravenous fentanyl, mean | 61.6 mL | 16.8 mL‡ | <.001 |
*
Patients randomly selected who had had surgery on the same day as cases but who had negative cultures of intravenous fluid from their infusion begun in the operating room.
†
Not significant at P < .05.
‡
For the nine control patients who received fentanyl.
From Maki DG, Klein BS, McCormick RD, et al: Nosocomial Pseudomonas pickettii bacteremias traced to narcotic tampering. A case for selective drug screening of health care personnel. JAMA 1991;265:981-986.
© 2008