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. 2009 May 15:1003–1069. doi: 10.1016/B978-032304841-5.50053-4

Table 51-4.

Estimated Extra Days, Extra Charges, and Deaths Associated with Nosocomial Infections in U.S. Hospitals as Reported in Recent Major Studies

Infection Description Average Extra Days in Hospital or ICU Per Infection Average Extra Charges or Costs per Infection ($) Excess Mortality
Unadjusted AttribuTable
Postoperative Surgical Wound Infection

Kirkland et al, 1999600 CABG, vascular surgery, abdominal surgery, orthopedic surgery 6.5 3,089 NR 4.3%

Whitehouse et al, 2002601 Orthopedic surgery 14 17,708 NR 0.0%

Hollenbeak et al, 2000602 Deep chest infection following CABG 20 20,012 NR 19.4%

McGarry et al, 2004603 All major surgical procedures; only S. aureus infections included 13 53,625 NR 16.8%

Herwaldt et al, 2006604 All major surgical procedures NR 3,021 1.2% 0%

Ventilator-Associated Pneumonia

Fagon et al, 1993605 Medical and surgical patients 13 NR NR 27.1%

Heyland et al, 1999606 Medical and surgical patients 4.3 NR NR 5.8%

Bercault et al, 2001607 Medical and surgical patients 5 NR NR 27.4%

Rello et al, 2002608 Medical and surgical patients 11 40,000 NR 0%

Warren et al, 2003609 Medical and surgical patients 25 11,897 16% NR

Cocanour et al, 2005610 Trauma patients 15 57,158 NR 0%

Bloodstream Infection

Pittet et al, 1994264 Surgical ICU 24 40,000 NR 35%

Digiovine et al, 1999265 Adult ICU 10 34,508 NR 4%

Slonim et al, 2001611 Pediatric ICU 22 35,000 NR 13%

Warren et al, 2006612 Adults 7.5 11,971 23% NR

Catheter-Associated Urinary Tract Infection

Bryan et al, 1984469 Medical and surgical patients NR NR NR 12%

Tambyah et al, 2002472 Medical and surgical patients NR 589 NR NR