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. 2010 Dec 29:26–455. doi: 10.1016/B978-0-443-07151-5.50005-6

Table 3.98.

Key considerations for dental management in leukaemia (see text)

Management modifications* Comments/possible complications
Risk assessment 3 Bleeding tendency; bacterial infections; anaemia; HCV, HBV and HIV infection

Appropriate dental care 3/4 Stage of disease life expectancy

Pain and anxiety control
 – Local anaesthesia 2 Avoid regional block; use chlorhexidine rinse
 – Conscious sedation 2 Methotrexate interacts with nitrous oxide
 – General anaesthesia 3–5 Avoid in severe anaemia

Patient access and positioning
 – Access to dental office 1 Coordinate with oncologist
 – Timing of treatment 1 Coordinate with oncologist
 – Patient positioning 0

Treatment modification
 – Oral surgery 3–5 Delay un til remission phase; full blood count; antibiotic cover; do not pack sockets
 – Implantology 3–5 See oral surgery
 – Conservative/Endodontics 3/5
 – Fixed prosthetics 3/5
 – Removable prosthetics 3
 – Non-surgical periodontology 3–5 See oral surgery
 – Surgical periodontology 3–5 See oral surgery
 – Orthodontics 3 Remove bands
 – Paediatric dentistry 3 Remove mobile primary teeth

Hazardous and contraindicated drugs 2 Avoid aspirin and NSAIDs; some patients receive corticosteroids
*

0 = No special considerations. 1 = Caution advised. 2 = Specialised medical advice recommended in some cases. 3 = Specialised medical advice mandatory. 4 = Only to be performed in hospital environment. 5 = Should be avoided.