Figure 7.2.5.

Paraquat poisoning. After initial swelling of the cytoplasm (A) the type I alveolar epithelial cells proceed to complete necrosis (B), exposing the basement membrane (arrow) they share with the alveolar capillary endothelium to alveolar air. Flecks of fibrin are seen in the alveolus. Intact endothelium and part of an erythrocyte are seen beneath the denuded basement membrane.

(Reproduced by permission of the editors of the Journal of Pathology⁹⁹and Progress in Respiratory Research.¹⁰³)