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Tablet filler materials in the lungs. (a) Intravascular and perivascular deposits of the tablet dispersant crospovidone eliciting a foreign-body giant cell reaction. (b) A crosprovidone granuloma stained with mucicarmine. (c) A starch granuloma stained with periodic acid–Schiff reagents. (d) The Maltese cross birefringence of starch viewed by polarized light.
(Courtesy of Dr JF Tomashefski Junior, Cleveland, USA.131)
