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. 2015 Jan 7;2015(1):CD003353. doi: 10.1002/14651858.CD003353.pub2

Heiselman 1995.

Methods RCT
Participants Number of participants randomised: 105; 46 in the control group and 59 in the metoclopramide group
Inclusion criteria: admission to the critical care unit; need for enteral nutrition
Did not state whether diabetic patients were included or not
Interventions
  • 59 participants received metoclopramide 10 mg intravenously 10 minutes prior to the insertion of the naso‐enteral tube

  • 46 control participants received no medication prior to the insertion of the naso‐enteral tube

Outcomes Success rate of post‐pyloric tube placement evaluated by auscultation of the right upper abdominal quadrant and abdominal radiography taken 45 minutes after tube advancement
Notes Setting: Ohio, USA
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk No details about randomisation provided
Allocation concealment (selection bias) Unclear risk Concealment of allocation sequence not described
Blinding (performance bias and detection bias) 
 All outcomes High risk No blinding of participants, personnel or outcome assessors
Incomplete outcome data (attrition bias) 
 All outcomes Low risk There were no withdrawals or dropouts
Selective reporting (reporting bias) Unclear risk All outcomes reported
Other bias Low risk Sample size calculation was reported