Figure 2.

Quantitative real-time PCR analysis for COX-2 mRNA expression in hepatocytes of treated and untreated rats with actin as housekeeping gene. Data analysed by one-way analysis of variance using graph pad prism 8. Asterisks **** indicate p < 0.0001 significance from control and vehicle group, ⁺⁺⁺⁺ indicates p < 0.0001 significance from cisplatin (CP 12 mg/kg) treated group and ^## indicate p < 0.01 significance difference between CP + T (20 mg/kg) and CP + T (40 mg/kg) treatment groups. T stands for compound 3 treatment.