Table 2.
Reaction time (s) post drug |
||||||||
---|---|---|---|---|---|---|---|---|
Treatment (n = 6) | Dose (mg/kg) | Reaction time (s) pre drug | 30 m | % Inhibition | 60 m | % Inhibition | 120 m | % Inhibition |
Compound 3 | 150 | 5.00 ± 0.36 | 4.83 ± 0.30 | 3.33 | 7.33 ± 0.42** | 46.66 | 7.16 ± 0.30*** | 63.33 |
Sulindac | 100 | 4.83 ± 0.40 | 5.50 ± 0.34 | 13.79 | 8.83 ± 0.79*** | 82.75 | 11.00 ± 0.57*** | 127.58 |
All values represent mean ± SEM. ANOVA, followed by Dunnett’s multiple comparison test.
**p < 0.01. ***p < 0.001.