Table 3.
Reaction Time (seconds) post drug |
||||||||
---|---|---|---|---|---|---|---|---|
Treatment (n = 6) | Dose (mg/kg) | Reaction Time (seconds) pre drug | 30 m | % Inhibition | 60 m | % Inhibition | 120 m | % Inhibition |
Compound 3 | 150 | 6.66 ± 0.33 | 7.66 ± 0.42 | 15 | 9.83 ± 0.30*** | 47.50 | 11.16 ± 0.30*** | 67.50 |
Sulindac | 100 | 7.66 ± 0.33 | 10.83 ± 0.47*** | 41.30 | 11.83 ± 0.47*** | 54.34 | 14.33 ± 0.42*** | 86.95 |
All values represent mean ± SEM. ANOVA, followed by Dunnett’s multiple comparison test.
***p < 0.001.