Table 3.

The antagonist effect on RXRα (EC₅₀) and cytotoxic effect on two normal cell lines (IC₅₀) of the selected compounds.^a

Compounds	EC50 (μM)	IC50(μM)
	RXRα	LO2	MRC-5
6c	ND	ND	ND
6e	ND	ND	ND
6k	1.05 ± 0.18	24.94 ± 1.40	>100
6A	1.68 ± 0.22	>100	>100
6B	7.23 ± 0.32	14.27 ± 1.16	>100
6C	1.75 ± 0.35	32.09 ± 1.51	>100
6D	ND	ND	ND
6E	ND	ND	ND
6F	27.69 ± 1.35	ND	ND
6G	0.56 ± 0.14	21.1 ± 1.32	>100
6H	0.54 ± 0.06	16.89 ± 1.22	>100

^aData are means ± SD of triplicate experiments.