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Overall-activated expression features of DE circRNAs responsive to MERS-CoV infection. (A) Number of clusters generated in the elbow method to select the optimal cluster number of DE circRNAs profiling. The summed distance of each circRNA from its cluster centroid was assessed and plotted. (B, C) Temporal profiles of the average expression pattern of DE circRNAs and the top 8 enriched KEGG pathways for each cluster.
