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Transport across the BBB of novel biomimetic nanosystems. (A) Schematic diagram of in vitro BBB model. (B) FCM analysis of HT22 cells treated with various Cou6-tagged formulations after crossing the BBB-HT22 cells co-culture in vitro model. (C) In vivo brain-targeting ability. Biodistribution of DIR contained in various formulations determined by IVIS Lumina II.
