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. 2020 Mar 31;27(1):502–518. doi: 10.1080/10717544.2020.1745328

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© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 7. — Therapeutic effect of RSV-loaded novel biomimetic nanosystems in vitro. FCM analysis of (A) mitochondrial ROS accumulation obtained by MitoSOX and (B) intracellular H₂O₂ level by CM-H₂DCFDA in Aβ_23–35-damaged HT22 cells after treatment with different RSV-loaded formulations. Changes of (C) MnSOD and (D) MDA levels in Aβ_23–35-damaged HT22 cells after treatment with different RSV-loaded formulations. (E) Apoptosis results of Aβ_23–35-damaged HT22 cells after treatment with different RSV-loaded formulations. The data are presented as the means ± SD (n = 3). * indicates p < 0.05.