Figure 5.
Effects of SMI on ADR distribution in MCF‐7/ADR cells. (A) Images of ADR distribution in MCF7/ADR with various concentrations of SMI (0.25, 0.5, 1 mg/mL) pretreat for 4 h and then incubated with 5 μM ADR for 30 min. Cell nuclei were stained with DAPI. Scale bar, 100 μm. (B) Fluorescence quantification of the ADR accumulation in nuclei. Data are the mean ± SEM of three independent experiments. *p < 0.05, compared with ADR control group.