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SMI reversed MDR of MCF-7/ADR cell via inhibition of MAPK/NF-κB pathway. (A,B) SMI inhibited the activation of MAPK pathway in MCF-7/ADR cells. (C,D) SMI inhibited the activation of NF-κB pathway in MCF-7/ADR cells. The protein level of p-ERK, p-JNK, P-IκBα, p-p65 was normalized to the level of tubulin, the loading control. Data are the mean ± SEM of three independent experiments. *p < 0.05 versus ADR group.
