Table 1.

Reported hit rates for the screening of libraries drugs

Target	Acronym	Hit rate (%)	Screened library (size)		No. of hits	Reference
Insulin-degrading enzyme	IDE	0.45	APTEEUS-Universite de Lille Library	1120	5	Leroux et al.42
Human 3-hydroxy-3-methyl-glutaryl-coenzyme A	HMG-CoA reductase	3.3	NIH Clinical Collections librarie	727	24	Bessoff et al.43
Aspergillus fumigatus chitinase A1	AfChiA1	0.08	Dundee Drug Discovery Unit diversity	59904	48	Lockhart et al.44
Dengue virus non-structural proteins NS3 and NS interaction	NS3/NS5	1.6	2P2I-Oriented Chemical Library	1664	26	Milhas et al.45
HIV virus Nef and Hck kinase interaction	Nef/SH3-Hck	0.2	2P2I-Oriented Chemical Library	1664	2	Milhas et al.45
HIV virus integrase and LEDGF/p75 IBD domain	IN/IBD	0.17	Protein kinase inhibitor library, REDOX library	578	1	This paper