Table 3.
Laboratory value | Baselinea | 12 weeksb | 24 weeksc |
Alanine aminotransferase (U/L) | n=2843 | n=2697 | n=2764 |
Normal (M<41, F<33) | 1028 (36.2) | 1427 (52.9) | 2095 (75.8) |
Abnormal (1–2 times upper limit) | 1286 (45.2) | 1127 (41.8) | 622 (22.5) |
>2 times upper limit | 529 (18.6) | 143 (5.3) | 47 (1.7) |
Aspartate aminotransferase (U/L) | n=2843 | n=2696 | n=2761 |
Normal (M<50, F<35) | 1487 (52.3) | 1907 (70.7) | 2464 (89.2) |
Abnormal (1–2 times upper limit) | 1162 (40.9) | 754 (28.0) | 278 (10.1) |
>2 times upper limit | 194 (6.8) | 35 (1.3) | 19 (0.7) |
Gamma-glutamyl transferase (U/L) | n=2076 | n=1936 | n=1964 |
Normal (M<49, F<32) | 827 (39.8) | 1017 (52.5) | 1228 (62.5) |
Abnormal (1–2 times upper limit) | 928 (44.7) | 759 (39.2) | 666 (33.9) |
>2 times upper limit | 321 (15.5) | 160 (8.3) | 70 (3.6) |
Data are expressed as n (%). Percentages are calculated as n/N.
P value (χ2 test with Benjamini-Hochberg correction for multiple comparisons): b vs a, p<0.001, c vs a, p<0.001, c vs b, p<0.001.
F, female; M, male.